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Geprüfter Lieferant Hota Supply 99% Tianeptine Acid Powder/Tianeptine Free Acid
Product Name:Tianeptine Acid
CAS:66981-73-5
MF :C21H25ClN2O4S
Grade Standard Pharmaceutical grade
Specification:99%min
Appearance:white powder
Tianeptin, a tricyclic compound, is a selective facilitator of 5-HT (serotonin; sc-201146) uptake in vitro and in vivo. Additionally, Tianeptin is reported to act as a selective inhibitor of dopamine uptake . Tianeptin does not have a noted effect on monoamine uptake. In a study utilizing purified synaptosomes from rat brain, Tianeptin was reported to enhance serotonin uptake in selective brain regions. Purified synaptosomes were obtained from rats and incubated with tritium-labeled 5-HT and Tianeptine in vitro . The synaptosomes were then analyzed for uptake and release of 5-HT via a liquid scintillation.
Function
Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).
Application
Tianeptine shows efficacy against serious depressive episodes (major depression), comparable to amitriptyline, imipramine and fluoxetine, but with significantly fewer side effects. It was shown to be more effective than maprotiline in a group of people with co-existing depression and anxiety. Tianeptine also displays significant anxiolytic properties and is useful in treating a spectrum of anxiety disorders including panic disorder, as evidenced by a study in which those administered 35% CO2 gas (carbogen) on paroxetine or tianeptine therapy showed equivalent panic-blocking effects. Like many antidepressants (including bupropion, the selective serotonin reuptake inhibitors, the serotonin-norepinephrine reuptake inhibitors, moclobemide and numerous others) it may also have a beneficial effect on cognition in people with depression-induced cognitive dysfunction.
Tianeptine sodium salt is a drug used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).
Test Report
Comany Information
HOTA wants to help its clients to feel that they have control over their own health. That is why, as a passionate company, we have supplied professional food supplements and plant extracts.
As yet, many people remain unaware that so much can be achieved through food, exercise and supplementation. And that is a missed opportunity, both for the individual and for society. That is why we ensure that our expert knowledge is widely accessible. We actively look for increased knowledge and we substantiate everything that we say, do and produce with scientific research.
We see a future with a better quality of life for everyone: Living Quality. Everything that we strive for has just one single goal: to give you better control of health.
HOTA is dedicated to ensuring every one of our customers enjoys the best in service and product quality. If you have any questions or concerns, our team is always available to help you out!
More Advantages:
1. Leading factory price
2. Huge range of product in stock
3. Research & Development
Our R&D team is continuously developing new product to meet the market.
4. Quality control
At HOTA Co., Ltd, this process is probably the most stringent of all. To us, quality is a commitment. It is a constant process and a continuous improvement.
5. OEM Service: Capsules or Tablets available
Safe, Secure Packaging - Full sealed
1-25kgs: Aluminium bag outside and double plastic bags inside
More than 25kgs: Fiber drum outside and plastic bags inside
Fast, Secure Shipping
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By Express |
By air |
By sea |
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Suitable for under 25kg |
Suitable for more than 25kg |
Suitable for more than 500kg |
Q1: When will my order be shipped?
A: Within 3 working days after the payment.
Q2: Can i get some samples?
A: Yes, contact me to know more about sample
Q3: How to confirm the Product Quality before placing orders?
A: Every product is with professional COA. Please be sure about the quality.
If any doubt, sample is available to you to be tested before large quantity order.
Q4: How to start orders or make payments?
A: Payment by T/T, Western Union,MoneyGram etc .
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